Masteron is a derivative of DHT, class 1 (binds strongly to the androgen receptor, AR), with anti-estrogenic activity.

Masteron (drostanolone propionate) is an anabolic steroid with anti-estrogenic activity (it was used to treat breast cancer in the 1980s) [1] and with a good fat burning effect, moderately androgenic and anabolic (anabolism / androgenicity: 62 / 25), which produces high quality aesthetic effects, so it is one of the preferred drugs for a contest definition or preparation cycle. Masteron does not aromatize, so effects such as retention, gynecomastia (-1 on the Haluch scale) [2] do not happen with this drug, on the contrary, drostanolone is shown to be reasonably effective in controlling these side effects. The possible side effects with this drug are associated with its androgenicity (acne, hair loss, etc.), but they are usually very mild and tolerated even at high doses (> 500mg per week).

Masteron is often compared with primobolan and proviron, both derived from DHT and with anti-estrogenic activity, and all are very mild in inhibiting the HPT axis. Masteron is anabolically superior to proviron [3], but considered to be slightly inferior to primobolan [4]. Because it is a class 1 steroid, Masteron has a good synergy with class 2 drugs (which act in ways not mediated by the androgen receptor), such as dianabol, hemogenin and stanozolol, so it can be an excellent combination with one of these drugs, in addition to testosterone [ 5].

Because it is a powerful drug for quality gains, very aesthetic, masteron is often used by many athletes in the last weeks of preparation for competition. The most efficient doses used are usually 300 to 500 mg per week, and because it has a short half-life (~ 2 days) [6], applications should be frequent, every 1-2 days for a better use of the drug . Women can also use this drug in doses of 100 to 150 mg per week with some risk of virilization.

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