DIANABOL (METHANDROSTENOLONE) - PROFILE

Dianabol (methandrostenolone) is a steroid in the testosterone family, 17 AA, class 2 (binds weakly to the androgen receptor, AR), with little affinity for SHBG.
D-bol is one of the most popular and powerful anabolic steroids for gains in muscle mass and strength (anabolism / androgenicity: 90-210 / 40-60). As it is a direct derivative of testosterone, it can undergo aromatization (by conversion to methyl estradiol) [1], and side effects such as high blood pressure, retention and gynecomastia (+2 on the Haluch scale) [2] are very common with this drug, in addition to the classic androgenic effects (acne, hair loss, etc.) and its hepatoxity (17 AA). Although aromatization generates these undesirable effects, it can also increase the levels of GH, IGF-1 and the proliferation of androgen receptors [3]. Dianabol is also able to increase potassium retention, which helps to counterbalance the effect of sodium retention generated by aromatization.
Despite being a very anabolic steroid, a favorite for kick start in Bulk cycles, the gains with this drug are not very high, due to the high water retention, and it is common to lose a large part of these gains in the post-cycle. Anyway, D-bol does not cause great suppression of the HPT axis and is an excellent anti-catabolic (inhibiting cortisol by up to 70% even at low doses), so I believe it is a good idea to add it in smaller dosages (~ 10-30mg per day) on bridges [4] or even for a while at the beginning of CPT, especially after a cycle with long half-life drugs, where it can help to secure gains while the hormonal axis is recovering.
Dianabol is generally used as a kick start drug for ~ 4 weeks in cycles aimed at gaining volume, and because it is a short half-life drug (~ 4-6 hours) its administration should be well distributed throughout the day, with more efficient doses on average ~ 50 mg per day [5]. Due to its virilizing effects even at low doses (~ 10mg) it is not a good choice to be used by women [6].
In addition to the oral version, some underground laboratories also market the injectable version, which has a half-life of ~ 24-36 hours and can be administered every 1-2 days.

Leave a comment